Loeb S, Roehl KA, Antenor JV, Catalona WJ, Suarez BK, and Nadler RB.
“Baseline Prostate Specific Antigen (PSA) Compared with Median PSA for Age Group as Predictor of Prostate Cancer Risk in Men Under 60 Years of Age”
Urology, February 2006; 67: 316.
Link: http://www.ncbi.nlm.nih.gov/pubmed/16442597
In the general US population, the median PSA level is 0.7 ng/ml in the 40’s and 0.9 ng/ml in the 50’s. Young men with a baseline PSA level above the age-specific median are at significantly greater risk of future prostate cancer diagnosis and aggressive disease. Baseline PSA at a young age is a stronger predictor of prostate cancer than race, family history or digital rectal examination.