Loeb S, Peskoe SB, Joshu CE, Huang WY, Hayes RB, Carter HB, Isaacs WB, Platz EA
“Do Environmental Factors Modify the Genetic Risk of Prostate Cancer?”
Cancer Epidemiology Biomarkers Prevention 2015; 24: 213. PMID: 25342390.
This study examined effect modification by environmental factors of the association between single nucleotide polymorphisms with prostate cancer risk. Among men at high risk for prostate cancer based on their genotype, use of selenium was associated with a lower risk of advanced prostate cancer, while aspirin, ibuprofen and vegetables were associated with lower risk of nonadvanced prostate cancer.