Loeb S, Vonesh EF, Metter EJ, Carter HB, Gann PH, and Catalona WJ. “What is the true number-needed-to-screen and treat to save a life with prostate-specific antigen (PSA) testing?” Journal of Clinical Oncology January 2011; 29: 464. Link: http://www.ncbi.nlm.nih.gov/pubmed/21189374 Although number needed to screen (NNS) and number needed to treat (NNT) are useful statistics to… Read More
Mullins JK and Loeb S. “Diabetes Mellitus and Prostate Cancer Risk.” Expert Review of Endocrinology and Metabolism November 2010; 5: 787.
Loeb S, Carter HB, Schaeffer EM, Ling SM, Kettermann A, Ferrucci L, and Metter EJ. “Bone Mineral Content and Prostate Cancer Risk: Data from the Baltimore Longitudinal Study of Aging.” BJU International, July 2010; 106: 28. Link: http://www.ncbi.nlm.nih.gov/pubmed/20067459
Loeb S, Kan D, Helfand BT, Gashti SN, Nadler RB, and Catalona WJ. “Is Statin Use Associated with Prostate Cancer Aggressiveness?” BJU International 2009, Nov 3 epub. Link: http://www.ncbi.nlm.nih.gov/pubmed/19888973
Ross AE, Loeb S, Landis P, Partin AW, Epstein JI, Kettermann A, Feng Z, Carter HB, and Walsh PC. “Prostate-specific antigen kinetics during follow-up are an unreliable trigger for intervention in a prostate cancer surveillance program.” Journal of Clinical Oncology, June 2010; 28: 2810. Link: http://www.ncbi.nlm.nih.gov/pubmed/20439642 PSA doubling time and PSA velocity are frequently used… Read More
Loeb S, Helfand BT, Kan D, Isaacs WB, and Catalona WJ. “Does Diabetes Mellitus Modify the Association between 17q12 Risk Variant and Prostate Cancer Aggressiveness?” BJU International, November 2009; 104: 1200. Link: http://www.ncbi.nlm.nih.gov/pubmed/19627283
Loeb S, Schaeffer EM, Trock BJ, Humphreys EB, Epstein JI, and Walsh PC. “What are the Outcomes of Radical Prostatectomy for High-Risk Prostate Cancer?” Urology 2009, Nov 19 epub. Link: http://www.ncbi.nlm.nih.gov/pubmed/19931898 Historically most men with D’Amico high-risk prostate cancer (clinical stage ≥T2c, biopsy Gleason score 8-10, or prostate-specific antigen >20 ng/mL) were treated with combined… Read More
Brawer MK, Loeb S, Partin AW, Yoshimura N, Chancellor MB, Roehrborn CG, Assimos DG, Nickel JC, Shuch B, Pouliot F, Belldegrun AS, and Shapiro E. “Best of the 2009 AUA Annual Meeting: Highlights from the 2009 Annual Meeting of the American Urological Association, April 25-30, 2009, Chicago, IL.” Reviews in Urology, Spring 2009; 11: 82.
Loeb S and Schaeffer EM. “Risk Factors, Prevention, and Early Detection of Prostate Cancer.” Primary Care Clinics of North America, September 2009; 36: 603. Link: http://www.ncbi.nlm.nih.gov/pubmed/19616157
Loeb S and Partin AW. “Randomized Trials of Selenium, Vitamin E, or Vitamin C for Prostate Cancer Prevention.” Reviews in Urology, Spring 2009; 11: 114. Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725311/
Trock BJ, Guo CC, Gonzalgo ML, Magheli A, Loeb S, and Epstein JI. “Impact of Tertiary Gleason Patterns on Biochemical Recurrence Following Radical Prostatectomy: Proposal for a Modified Gleason Scoring.” Journal of Urology, August 2009 epub. Link: http://www.ncbi.nlm.nih.gov/pubmed/19683280
Loeb S, Epstein JI, Humphreys EB, and Walsh PC. “Does Perineural Invasion on Prostate Biopsy Predict Adverse Prostatectomy Outcomes?” BJU International, August 2009 epub. Link: http://www.ncbi.nlm.nih.gov/pubmed/19694710
Loeb S, Carter HB, Walsh PC, Isaacs WB, Kettermann A, Tanaka T, Ferrucci L, and Metter EJ. “Single Nucleotide Polymorphisms and the Likelihood of Prostate Cancer at a Given Prostate-Specific Antigen Level.” Journal of Urology, July 2009; 182: 101. Link: http://www.ncbi.nlm.nih.gov/pubmed/19450841 Genotype influences the risk of prostate cancer per unit increase in PSA. Prostate cancer… Read More
Helfand BT, Loeb S, Meeks JJ, Fought AJ, Kan D, and Catalona WJ. “Pathological Outcomes Associated with the 17q Prostate Cancer Risk Variants.” Journal of Urology, June 2009; 181: 2502. Link: http://www.ncbi.nlm.nih.gov/pubmed/19371897
Schaeffer EM, Carter HB, Kettermann A, Loeb S, Ferrucci L, Landis P, Trock BJ, and Metter EJ. “Prostate Specific Antigen Testing Among the Elderly: When to Stop?” Journal of Urology, April 2009; 181: 1606. Link: http://www.ncbi.nlm.nih.gov/pubmed/19246059 Men ages 75-80 with PSA levels <3 ng/ml are unlikely to die of or experience aggressive prostate cancer during… Read More
Loeb S and Partin AW. “Single Nucleotide Polymorphisms and Prostate Cancer Susceptibility.” Reviews in Urology, Fall 2008; 10: 304. Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615108/
Helfand BT, Loeb S, Cashy J, Meeks JJ, Thaxton CS, Han M, and Catalona WJ. “Tumor Characteristics of Carriers and Noncarriers of the deCODE 8q24 Prostate Cancer Susceptibility Alleles.” Journal of Urology, June 2008; 179: 2197. Link: http://www.ncbi.nlm.nih.gov/pubmed/18423739
Loeb S and Catalona WJ. “Counterpoint: the case for active treatment.” Journal of the National Comprehensive Cancer Network, August 2007; 5: 699. Link: http://www.ncbi.nlm.nih.gov/pubmed/17692174
Loeb S and Catalona WJ. “Early versus delayed intervention for prostate cancer: the case for early intervention.” Nature Clinical Practice Urology, July 2007; 4: 348. Link: http://www.ncbi.nlm.nih.gov/pubmed/17563779
Roehl KA, Eggener SE, Loeb S, Smith ND, Antenor JAV, and Catalona WJ. “Survival Results in Screen-Detected Prostate Cancer Patients Versus Physician-Referred Patients Treated With Radical Prostatectomy: Early Results.” Urologic Oncology: Seminars and Original Investigations 2006; 24: 465. Link: http://www.ncbi.nlm.nih.gov/pubmed/17138126
Loeb S, Yu X, Roehl KA, Antenor JV, Han M, and Catalona WJ. “Lymphovascular Invasion in Radical Prostatectomy Specimens: Prediction of Adverse Pathology and Biochemical Progression” Urology, 2006; 68: 99. Link: http://www.ncbi.nlm.nih.gov/pubmed/16806410
Loeb S, Gonzalez CM, Roehl KA, Han M, Antenor JV, Yap RL, and Catalona WJ. “Pathologic Characteristics of Prostate Cancer Detected Through Prostate-Specific Antigen- Based Screening” Journal of Urology 2006; 175: 902. Link: http://www.ncbi.nlm.nih.gov/pubmed/16469576
Roehl KA, Loeb S, Antefnor JA, Corbin N, and Catalona WJ. “Characteristics of Patients with Familial Prostate Cancer Versus Sporadic Cases.” Journal of Urology, December 2006; 176: 2438. Link: http://www.ncbi.nlm.nih.gov/pubmed/17085123
Loeb S, Roehl KA, Antenor JV, Catalona WJ, Suarez BK, and Nadler RB. “Baseline Prostate Specific Antigen (PSA) Compared with Median PSA for Age Group as Predictor of Prostate Cancer Risk in Men Under 60 Years of Age” Urology, February 2006; 67: 316. Link: http://www.ncbi.nlm.nih.gov/pubmed/16442597 In the general US population, the median PSA level is… Read More